Allergic pharyngolaryngitis after taking five days of loratadine effect is not obvious, the main consideration is related to the failure to get rid of allergens, improper use of medication and the degree of the disease, should be timely out of the allergic environment, and consider under the guidance of a doctor to change the drug or to take other medical measures to intervene. 1. Failure to detach from allergens: Failure to diagnose the allergens, resulting in the patient still being in the allergic environment, and after the application of drugs, the condition cannot be improved. In this case, the allergens should be identified and removed from the allergy-inducing environment. 2. Improper medication: Insufficient dosage of medication or intermittent medication may affect the efficacy of the medication. In this case, the medication should be adjusted in time. If necessary, you can also consider replacing other anti-allergy drugs, adding nebulized inhalation therapy, hormone therapy and other treatment modalities under the guidance of a doctor. Patients with contraindications to hormone application are prohibited from using hormones. The persistence of symptoms after the use of medication has not been relieved, and is related to a variety of factors. It is recommended to consult a doctor to confirm the diagnosis, and further treatment under the guidance of the doctor.