Cerebral leukodystrophy is most commonly ischemic, inflammatory, and metabolic. 1. In general, ischemic cerebral leukodystrophy is not curable; it is a demyelination of cerebral white matter that occurs from chronic ischemic and hypoxic damage, and the lesions have formed, and will become more and more numerous as the disease progresses and ages. To actively target risk factors, such as hypertension, hyperglycemia, hyperlipidemia for control, can slow down the progression of the disease. 2, inflammatory cerebral white matter disease can be partially cured, such as ADEM, also known as acute disseminated encephalomyelitis, but also some multiple sclerosis, optic neuromyelitis caused by immune inflammation, the patient after hormone shock therapy or gammaglobulin shock therapy, inflammation is controlled, the late The patient can be treated with hormone shock therapy or propaglobulin shock therapy to control the inflammation, and then given nutritional neurological symptomatic treatment, the lesion can mostly be relieved, but some diseases have a multi-phase course and are prone to recurrence. 3, metabolic cerebral leukodystrophy can be cured in a few cases, such as vitamin B1 deficiency caused by Wernicke’s encephalopathy, as long as the timely treatment of vitamin supplementation, there is a possibility of cure. But congenital genetic defects caused by metabolic encephalopathy, such as adrenoleukodystrophy, heterozygous cerebral leukodystrophy, etc. is not possible to cure.