Under normal circumstances, patients should not drink alcohol while taking cold medicine, at least 3 days after stopping the medicine to avoid accidents. If alcohol is consumed during a cold, it is not conducive to the efficacy of the medicine and is not conducive to the healing of the cold. The vast majority of cold medicines contain acetaminophen and other non-steroidal anti-inflammatory drug ingredients, in taking non-steroidal anti-inflammatory drugs during the period to strictly abstain from alcohol, because: 1, non-steroidal anti-inflammatory drugs in the body when the conversion of toxic metabolites, these metabolites need to be combined with glutathione in order to reduce the toxicity of alcohol can be consumed in large quantities of glutathione, the metabolites produced by non-steroidal anti-inflammatory drugs, due to the lack of glutathione, will increase the liver in the processing of metabolites, but also to reduce the toxicity of the metabolic properties of the drug. The metabolites produced by NSAIDs, due to the lack of glutathione, will increase the stress on the liver in processing the metabolites, thus increasing the risk of liver failure. 2. NSAIDs are irritating to the mucous membranes of the digestive tract, and alcohol will also irritate the mucous membranes of the gastrointestinal tract. If the digestive system itself is not functioning well, the double stimulation of NSAIDs and alcohol may even cause peptic ulcers or bleeding. In addition, during a cold there is also the possibility of taking antibiotics at the same time to treat respiratory tract infections, while taking antibiotics should also strictly abstain from alcohol. Patients need to pay special attention to, if you are taking cephalosporin antibiotics, to strictly abstain from alcohol, otherwise it will produce disulfiram-like reaction and other side effects, serious cases can be life-threatening. At the same time during the medication to eat a light diet, avoid spicy, stimulating food, so as not to affect the effectiveness of the drug.