Malignant polyps in the duodenal bulb can be treated by surgical removal and other means. The cost is usually around 10,000-50,000 RMB, and the specific treatment cost will fluctuate according to the surgical method, the severity of the disease and the grade of the hospital. Duodenal polyps mainly originate from mucosal epithelial tissue, most patients do not have obvious clinical symptoms, but as the polyps continue to grow, patients may experience epigastric discomfort, pain, nausea, vomiting, weight loss, anemia, and other symptoms, related to heredity, bacterial and viral infections, bile reflux, environment and other factors. When duodenal polyps become cancerous, there are different surgical options for treatment. Endoscopic resection, for patients with small duodenal polyps; open resection, for duodenal polyps that are difficult to remove endoscopically. Patients should not eat immediately after surgery, and avoid strenuous exercise, keep the surgical site clean and dry to avoid infection. Patients with malignant duodenal polyps are advised to seek timely medical attention for a clear diagnosis and targeted treatment under the guidance of a doctor.