Status epilepticus (SE) is the most severe form of seizures and is a common neurological emergency. Persistent epileptic seizures may not only cause disruption of cellular metabolism and impaired energy supply leading to brain neuron death, but also lead to patient death due to secondary infection, disturbance of internal environmental balance, respiratory and circulatory failure, etc. Survivors may also be left with severe neurological dysfunction or develop drug-resistant epilepsy. Based on the clinical manifestations, the patients are classified into Convulsive Status Epilepticus (CSE) and Nonconvulsive Status Epilepticus (NCSE) based on the presence or absence of strong skeletal muscle contractions during seizures. In addition, the EEG was divided into partial SE and generalized SE, and then referred to as partial status epilepticus and generalized status epilepticus according to the claim of the International League Against Epilepsy in 1981. The exact definition of refractory status epilepticus (RSE) is unclear because different studies have defined refractory status epilepticus using different duration (no time standard, 30 minutes, 1 hour, 2 hours) and lack of criteria for the type and amount of medication used, the current clinical standard of >2 hours is generally used. Super-refractory status epilepticus (SRSE) refers to SE with persistent seizures or recurrences for not less than 24 hours after initiation of narcotic medication, and recurrences after withdrawal or reduction of narcotic medication.