The common cause of knee pain after drinking is gouty knee arthritis, and gouty arthritis causes pain, mainly because of increased uric acid. The reasons for knee pain after drinking can be the following: 1. Alcohol is metabolized by the kidneys before it can be excreted, and the excretion of uric acid produces mutual resistance, when gout patients ingest alcohol the kidneys will give priority to metabolize alcohol, making it difficult to excrete uric acid. 2. Alcohol itself will promote the breakdown of purines in the body into uric acid, alcohol in white wine and beer does not contain high purines, but contains The liver can produce a large amount of uric acid when metabolizing ornithine. Gout patients should limit their alcohol intake to avoid triggering gout attacks.