Side effects of gliclazide include hypoglycemic reaction, gastrointestinal dysfunction, skin and subcutaneous tissue reactions, etc. There is no such thing as a maximum side effect. 1. Hypoglycemic reaction: it is the most common adverse reaction of gliclazide, in the case of irregular meal time, or missing one or several meals, taking gliclazide may lead to the occurrence of hypoglycemia, and dizziness, weakness, drowsiness, coma, and death may occur. 2. Gastrointestinal disorders: abdominal pain, nausea, vomiting, indigestion, etc. may occur. By taking gliclazide with breakfast, these symptoms may be avoided or the risk minimized. 3. Skin and subcutaneous tissue reactions: rash, itching, urticaria, angioedema, etc. may occur. Gliclazide is a common hypoglycemic drug, allergy to Gliclazide, type 1 diabetes mellitus is prohibited, if you need to take Gliclazide, you should standardize the use of medication under the guidance of a doctor.