Lupus erythematosus easily invades women of reproductive age, with a male to female ratio of about 1:9. The earliest appearance is the damage to the skin mucosa, with an incidence of about 70%-80%, and some patients have the first symptoms. The most common mucosal damage is mainly oral ulcers, and the following manifestations can be seen on the skin: 1. butterfly erythema, butterfly-shaped edematous erythema distributed on the cheeks and nasal bridge, aggravated by sun exposure, which is the characteristic lesion. 2. discoid erythema, more common in men. 3. small petechiae can be seen on the ends of the hands and feet, with purpura-like manifestations. 4. alopecia, if the disease is active, the scalp can be seen Diffuse alopecia, a small number of patients in the forehead of the hair, you can see the hair is relatively thin, no luster, often at 2-3cm break on their own, forming an appearance like a brush. more than 90% of patients will have varying degrees of joint pain, muscle aches and pains, etc. The above are common early symptoms.