The causes of itchy blisters on the patient’s body are mainly considered as follows: 1. Herpes of pregnancy: Pregnancy may cause autoimmune skin diseases due to low immunity of the organism, and erythema and blisters with itching may appear on the extremities and abdomen of pregnant women in 4-6 months of pregnancy. Also, after immunofluorescence testing in dermatology, it is possible to see IgG and C3 deposited in the epidermis, at which point the diagnosis of herpes in pregnancy can be made. In terms of treatment, patients usually do not require treatment and can resolve naturally after delivery. If the patient has significant itching, a topical stove glycolic lotion can be used. If the patient’s blisters rupture, accompanied by itching increasingly aggravated, you can apply compound cypress lotion local cold, and topical comfrey oil and recombinant human epidermal growth factor gel, but also oral calcium carbonate chewable tablets, during treatment need to instruct patients to pay attention to rest. 2, papular urticaria: an allergic skin disease caused by mosquito bites, on the body can be seen like a mosquito bite red bun, the center can appear blisters , accompanied by itching. In the treatment, you can apply compound glycopyrrolate tablets and levocetirizine hydrochloride tablets. For topical application, a mixture of mometasone furoate cream and urea vitamin E cream can be applied topically. During the treatment period, patients need to abstain from spicy and irritating foods and must apply topical insect repellent drops or ointments when going out. Therefore, for patients with blisters on the body with itching, it is recommended to go to a regular hospital and undergo appropriate laboratory tests under the guidance of a dermatologist to guide clinical treatment.