High uric acid and high blood creatinine are not necessarily renal insufficiency, which is divided into physiological and pathological conditions, physiological ones are seen in the consumption of high-purine food, a large number of meat and so on. Pathologic may suggest renal insufficiency. Physiological: after consuming high purine food, uric acid may rise; after consuming a large amount of meat, creatinine may rise, and may return to normal after controlling the diet. Pathological: blood creatinine is an indicator for evaluating glomerular filtration function, uric acid is also excreted through the kidney, glomerular filtration rate decreases in patients with renal insufficiency, and blood creatinine and uric acid may be elevated. If you find high uric acid and high blood creatinine, you should go to the hospital in time, clarify the cause of the disease under the guidance of professional physicians, and follow the doctor’s instructions for treatment in time.