When bedsores form in the elderly, they are mainly treated with topical medications that can relieve pain, promote wound healing and avoid further infection. The following drugs are usually used for the treatment of bedsores in the elderly: 1) cauterizing cream: it is a commonly used drug for the clinical treatment of bedsores, which can be applied to the affected area to drain pus, extract toxins, remove decay and produce skin. 2.Zinc oxide ointment of boric acid: it is often used clinically as an adjunctive treatment for bedsores and burns, and occasional skin irritation, such as burning sensation, rash, itching, etc., should be discontinued; 3.Erythromycin ointment: it is suitable for ulcerated and infected skin, and can be applied to the affected area in appropriate amounts to relieve the spread of bedsores; 4.Rehabilitation new liquid: it is a Chinese medicinal preparation that can be used orally and externally to treat bedsores. It is prohibited and may cause skin redness and pain, rash, itching, dizziness, difficulty in breathing or adverse reactions of the digestive system, such as nausea and vomiting. It should be noted that no matter what drugs are used, it is necessary to consult a professional physician to avoid drug interactions, reduce the possibility of allergy occurrence, stop the drug immediately if an allergic reaction occurs, and seek medical attention promptly. Daily disinfection treatment of decubitus ulcers should be done in order for the drugs to work effectively. It is also necessary to avoid local compression, use decubitus pads or air cushions, turn over regularly, and keep the decubitus ulcer site clean and with good blood supply. Enhance nutrition, supplement protein, and avoid spicy and stimulating foods such as onion and ginger, pepper, etc., to strengthen the body’s resistance.