Cold hoarseness is mostly considered to be the result of acute inflammation caused by colds spreading to the vocal cords, causing congestion and edema of the vocal cords, affecting their vibratory frequency and leading to a hoarse voice. Colds are acute upper respiratory tract infections caused by viruses, and the upper respiratory tract includes the trachea, nasal passages and throat. Generally speaking, most of them are accompanied by an uncomfortable reaction in the throat. Acute inflammation caused by viruses leads to congestion and edema in the throat, which may spread to the vocal cords. Combined or secondary bacterial infections can trigger pharyngitis and vocal cord inflammation, and patients manifest hoarseness and sore throat. In terms of treatment, if the patient’s symptoms are mild, it is necessary to treat the cold, and the edema of the vocal folds will be relieved with the improvement of the cold; in severe cases, it is necessary to treat the symptoms with glucocorticosteroids, such as budesonide, by nebulized inhalation. If there is a clear combination of bacterial infection, antibiotics such as cefaclor are needed. It is recommended that the patient go to the hospital in time to improve the blood routine and other related examinations, to exclude other diseases that cause hoarseness of the voice, a clear diagnosis, and reasonable and standardized treatment for the cause.