Norethindr is the trade name of goserelin acetate extended-release implant. Male injections are mainly used for the treatment of prostate cancer, which can make men’s libido disappear, and long-term injections can even affect men’s sexual function, which can be done without considering contraception. Female injections are generally used to treat breast cancer, endometriosis and other diseases, and will not interfere with the union of sperm and egg, and contraception is needed during the use of the drug. 1. Men: male prostate cancer patients, after treatment with goserelin acetate extended-release implant, can inhibit testosterone secretion, so that the testosterone level is extremely low, and may lose sexual desire, so that the penis cannot be erected, at which time sexual life cannot be completed, and cannot be performed during the use of the drug The drug can not be used during sexual life, so there is no need to consider the issue of contraception; 2, women: Goserelin acetate extended-release implant has a certain inhibitory effect on ovarian function, but can not play a role in contraception, during the use of the drug still need to take contraceptive measures, especially when menstruation is not regular, consider condom contraception, avoid excessive use of drugs, if pregnancy, lactating women, it is contraindicated to use the drug. In addition, goserelin acetate extended-release implant should not be used by minors in general, and if the condition requires it, a specialist should be consulted. Side effects such as facial flushing and peripheral fever may occur during use and should be regular according to the course of treatment. They usually resolve on their own and do not require special treatment and regular follow-up.