The use of Povidon suppositories during the early stages of pregnancy may cause the possibility of preterm or inevitable miscarriage. This is because if the medication is not administered properly it may stimulate to cause uterine contractions that can lead to abruption between the gestational sac and the uterine wall, and vaginal bleeding may occur. Therefore, it is advisable not to insert medication into the vagina during the early stages of pregnancy. If there is an increase in vaginal discharge, vulvar itching, or yellowish vaginal discharge, it is advisable to go to the hospital in time to get the appropriate tests to find out which kind of bacteria is causing the vaginal infection through laboratory tests, and then give the appropriate medication for treatment. It is also recommended to use medication only under the guidance of a doctor. In the early stages of pregnancy, vaginal plugs are not recommended, but oral medication can be used.