There is no uniform chemotherapy regimen for small cell neuroendocrine carcinoma of the uterine cervix, and the most commonly used chemotherapy regimen is platinum combined with etoposide regimen. Small cell neuroendocrine carcinoma of the uterine cervix is a rare type of malignant tumor of the uterine cervix, which is most often treated with a combination of surgery, chemotherapy and radiotherapy. Surgery supplemented with chemotherapy can reduce pelvic recurrence and improve survival. The most commonly used regimen is cisplatin or carboplatin combined with etoposide glyburide or irinotecan, which can be used for early-stage disease postoperatively, neoadjuvant chemotherapy for locally advanced disease, and chemotherapy after radiotherapy. Chemotherapy can improve the survival of small cell neuroendocrine carcinoma of the cervix, and the specific chemotherapy program should be selected by professional doctors for specific cases and strictly implemented according to the doctor’s instructions.