Differences between Lizhong Wan and Lizhong Wan with Radix et Rhizoma Polygoni Multiflori are: drug composition, efficacy and main treatment, and precautions are different. 1. Composition: Lizhong Pill is composed of boiled ginger, ginseng, roasted licorice, and atractylodes macrocephala. The other pill consists of Radix Rehmanniae Praeparata, Radix et Rhizoma Ginseng, Radix et Rhizoma Ginseng, Rhizoma Atractylodis Macrocephalae, Rhizoma Glycyrrhizae. 2. Efficacy and Indications: Lizhong Pill has the efficacy of warming the middle and dispersing the cold (dispersing the cold with medicine that warms the spleen and stomach), strengthening the stomach, and treating patients with spleen and stomach deficiency and cold (spleen and stomach weakness and cold), which can be seen in vomiting, diarrhea, indigestion, loss of appetite, chest fullness (chest fullness and discomfort), abdominal pain, and other symptoms. Radix Rehmanniae Pill has the effect of warming the middle and strengthening the spleen, and is suitable for patients with hypothermia of hands and feet, vomiting and diarrhea, cold pain in the epigastric region (cold pain in the stomach and abdomen) caused by coldness in the spleen and stomach. 3. Lizhong Pill is not suitable for patients with diarrhea, vomiting and stomach pain caused by damp-heat obstruction (accumulation of damp and heat evils to form stasis). Patients with cold and fever should not take Radix Rehmanniae Pill, pregnant women should be cautious, and should not overdose or take this product for a long time. It is not recommended to consume raw, cold and indigestible food during the use of Lizhong Pill or Radix Rehmanniae Pill. It is necessary to use Lizhong Pills or Lizhong Pills with Conjugated Zi under the guidance of a professional Chinese medicine practitioner, and should not be used blindly.