Eating seafood allergy rash may be hives, the first is to avoid eating allergic food, followed by giving systemic medication, topical medication and other treatments. Urticaria rash manifests itself as reddish reddish red bumps of varying sizes, accompanied by itching, and lasts for generally less than 24 hours. It can be triggered by food, and common food allergens include animal proteins such as fish, shrimp and crab. Treatment involves avoidance of food allergens and avoidance of seafood or seafood-containing foods. Oral antihistamines such as loratadine, cetirizine, ebastine, etc. can be used for treatment, and vitamin C, calcium gluconate, etc. can be used as topical glycerine lotion to relieve itching. Patients need to go to the hospital, follow the doctor’s instructions for treatment, the application of drugs need to strictly follow the doctor’s instructions, do not self-medication.