HPV59 refers to human papillomavirus type 59, which can be improved by medication, physical therapy, and surgery. 1. Medication: Use anti-viral medication under doctor’s supervision, such as interferon gel, interferon suppositories, etc. for vaginal administration to enhance the local infectious force of the vagina and cervix, as well as ganciclovir, acyclovir, etc. to promote the recovery of the infection. 2. Physical therapy: If HPV59 is positive and low-grade lesions are present, laser, microwave, freezing and electrocautery can be used to make the cervical lesions crust and necrolysis off, repair the trauma and get treatment. 3. Surgical treatment: if HPV59 high-risk positive, and cervical intraepithelial neoplasia, according to the patient’s condition, you can choose radiofrequency ablation surgery, Lipstick surgery and other treatments, and pay attention to keep personal cleanliness after the operation. It is recommended that patients go to the hospital regularly to do liquid-based thin-layer cell test for cervical cancer screening.