There are reversible and irreversible methods of nerve block therapy. Nerve blocks using conventional local anesthetics are generally reversible and are also referred to as chemical nerve block therapy. The commonly used local anesthetics are procaine, lidocaine, bupivacaine and ropivacaine, etc. 0.25%~1.0% procaine solution is suitable for superficial tissue nerve block; lidocaine is a medium-acting local anesthetic, and 0.25%~1.0% injection is commonly used for nerve block; bupivacaine is a long-acting local anesthetic with strong anesthetic properties, slow onset and long duration of action (5~6 hours), so it is commonly used for chronic pain treatment, postoperative analgesia and cancer treatment. It is often used in chronic pain treatment, postoperative analgesia and cancer pain treatment. Ropivacaine is a new type of long-acting amide local anesthetic, which has low cardiotoxicity and good tolerance of the central nervous system compared with bupivacaine, and is especially suitable for painless delivery and obstetric analgesia, with a common concentration of 0.2%. Glucocorticoids are often used in chronic pain treatment because of their ability to reduce the inflammatory response and immunosuppressive effects, and are commonly used in clinical practice, such as prednisone, dexamethasone and betamethasone. Glucocorticoids are contraindicated in patients with combined hypertension, diabetes mellitus, ulcerative disease and acute septic inflammation. Irreversible methods of nerve block refer to methods that permanently destroy nerve fibers and block pain transmission, such as the application of physical nerve block methods like surgery, radiofrequency, cooling or pressure, and chemical nerve block methods like nerve-destroying drugs.