Intractable insomnia belongs to the category of insomnia disease in Chinese medicine, which is clinically considered to be related to the factors of disturbing the heart by evil heat and deficiency of the heart and spleen (weakness of the heart and the spleen), etc. The prescriptions include gentian diarrhea and liver soup, Huanglian and warm gallbladder soup, and Guisheng and spleen soup. 1. Liver-heat disturbing the heart syndrome: it can be seen as sleeplessness and dreamy, or even sleeplessness all night, irritability, accompanied by dizziness and head distension, dry and bitter mouth, constipation, ulcer and redness, etc. It is necessary to dredge the liver and diarrhea, and calm the heart. It is necessary to dredge the liver and diarrhea fire, calm the heart and tranquilize the mind, and can be treated with gentian diarrhea liver soup or Angelica Longhui Pill with additions and subtractions. 2. Phlegm-heat disturbing the heart syndrome: it can be seen as disturbed heart and insomnia, chest tightness and epigastric plumpness, nausea, bitter mouth, etc. It is necessary to clear away heat and resolve phlegm, harmonize the middle and lower parts of the body, and treat the symptoms. It is necessary to clear away heat and resolve phlegm, harmonize the middle and tranquilize the mind, and can use Huanglian Wengdian Tang with additions and subtractions. 3. Deficiency of the heart and spleen: insomnia, waking up with dreams, palpitations (rapid heartbeat, often accompanied by panic), forgetfulness, fatigue (lack of energy), poor appetite, abdominal distension and loose stools (loose stools), and a less colorful complexion, etc. The patient needs to tonify the heart and spleen (using nourishing and nourishing agents). It is necessary to tonify the heart and spleen (using nourishing drugs to tonify the heart and spleen), nourish the blood and calm the mind (stabilizing the mind and soothing the emotions by nourishing the blood), and can use Gui Spleen Tang with additional subtractions. If persistent insomnia occurs, one should go to the hospital in time for standardized treatment under the guidance of a doctor.