Patients with high altitude headache can take ibuprofen for symptomatic relief of the headache. High-reflex headache refers to the patient from the plain area into the plateau area triggered, generally not too serious, when the lung ventilation increases, the patient open mouth breathing symptoms can be relieved. Patients are advised to take more rest and avoid activities, and can generally take ibuprofen, acetaminophen, painkillers and indomethacin to relieve headache symptoms. The headache caused by high altitude reflex is mainly manifested in the frontal and bilateral temporal areas, and the pain symptoms pain is more obvious, usually at night or in the morning when the headache is aggravated. Patients with high altitude reflex must perform adaptive exercises before entering the plateau, and if necessary, adjust the patient’s blood oxygen by inhaling oxygen, etc.