Chest pain in the middle of the chest may be caused by trauma, costochondritis, coronary heart disease, gastroesophageal reflux and other conditions, according to the specific circumstances of the surgical treatment or medication to alleviate the condition, the use of medication in accordance with medical advice. 1. Trauma: If the chest is traumatized, rib fracture or local soft tissue contusion, hematoma, etc., it will be manifested as chest pain, chest tightness and other symptoms. Non-steroidal anti-inflammatory drugs, such as ibuprofen, can be taken if the pain is severe. Those with hemothorax or pneumothorax need closed chest drainage. Open fracture or the condition requires surgical treatment. 2. Costal chondritis: viral infection in the costal cartilage tissue may lead to local inflammation, which may damage the peripheral nerve tissues leading to boring pain in the middle of the chest, non-steroidal anti-inflammatory drugs such as ibuprofen, etc., and local closure, such as the use of lidocaine, etc., can be used in cases of severe pain. If the effect of non-surgical treatment is unsatisfactory, surgery can be performed to remove the diseased rib cartilage. 3. Coronary heart disease: caused by narrowing or occlusion of coronary artery lumen, manifested as chest pain, chest tightness, chest tightness and so on. Nitrate drugs such as nitroglycerin can be taken. Surgical treatment, including percutaneous coronary intervention and coronary artery bypass grafting, may be needed. 4. Gastroesophageal reflux: when the smooth muscle of gastroesophageal reverse peristalsis occurs, it will make the gastric acid reflux into the esophagus, which will erode the mucosa of esophagus and lead to the symptoms of chest pain, etc. It can be treated with acid-suppressing treatment, such as omeprazole, etc. If the symptoms are serious, surgery is feasible. If the symptoms are serious, surgical treatment is feasible, such as laparoscopic fundoplication. There are other causes of chest pain in the middle of the chest, it is recommended that patients seek timely medical treatment, so as to avoid delaying the condition.