Usually for patients with coronary artery disease who wake up while sleeping, there are several possibilities as follows: First, the past history of coronary artery disease may show incomplete and insufficient blood supply to the coronary arteries while sleeping, such as transient stenosis or spasm of coronary arteries, contracture of coronary atherosclerotic plaques or spasm of blood vessels, resulting in ischemic conditions, and in the case of ischemia, there will be clinical symptoms and feelings of being awakened while sleeping. Second, patients with coronary artery disease may also experience ischemia. Secondly, patients with coronary artery disease may also suffer from cerebrovascular insufficiency of blood supply, and may be awakened by suffocation if cerebrovascular insufficiency of blood supply. Third, there will also be a lack of oxygen, and lack of oxygen will also lead to wake up, for example, the arterial oxygen saturation is not enough, then there will also be obvious clinical manifestations of suffocating in sleep. Regardless of the reason for patients with coronary artery disease to wake up with suffocation during sleep, it is recommended to go to the hospital for a detailed examination to check the heart and lung function.