Mr. Cai from Shanghai, 37 years old, height 1.69m, weight 90kg, BMI 31.51kg/m2, it is hard to imagine that he was a handsome guy in the past. He said that since he got married, his weight has gone up, and slowly various complications such as hyperlipidemia, fatty liver, gout, etc. have appeared one after another, in which he tried various ways to lose weight, fitness, slimming tea, diet pills, liposuction, etc., are effective at first, once stopped, the weight rebounded quickly, and the more fat loss, gradually he also lost confidence, allowing the weight to climb. 2012 In April 2012, he found out that his blood sugar was high and his glucose tolerance was abnormal, and he started taking glucose-lowering drugs. Lao Cai’s father had been suffering from diabetes for decades and now had multiple complications of diabetes, and his quality of life was extremely poor, which scared Lao Cai and his wife. After seeing the report of Shanghai TV about the surgery for obesity and diabetes in Shanghai Sixth Hospital, his lover searched for relevant information on the Internet and came to the endocrinology ward of Shanghai Sixth Hospital to learn about the effectiveness and safety of this minimally invasive surgery from the mouths of patients who had already had the surgery. After the preoperative examination and surgical evaluation in the endocrinology department, Professor Zhang Pin performed the laparoscopic gastric bypass surgery for Cai. The surgery went very well and to Lao Cai’s surprise, his blood glucose started to drop in the first week after the surgery and by the time he was discharged from the hospital after the surgery, it had already dropped to the normal range, and his weight was also gradually decreasing, and at the follow-up visit in March after the surgery, his weight had dropped to 75 Kg and his glycated hemoglobin was 6.4%. Director Zhang explained that gastric bypass reconstructed the order of digestive tract in the body, so that the originally disordered endocrine hormones were regulated and rebalanced, and the insulin resistance was significantly relieved, so that the phenomenon of blood glucose decrease would soon appear and take priority over the weight loss. Now Lao Cai is 1.5 years postoperative, with a body mass index of 24 kg/m2, completely normal blood sugar, improved gout for many years, disappeared hyperlipidemia, and normalized fatty liver. At a meeting of sugar diabetic patients, he excitedly said that he was grateful to his loved ones for their care, consideration and attention, and to the team led by Director Zhang Pin for getting rid of obesity and diabetes and allowing him to lead a happy life again.