Generally speaking, 49-year-old women have already entered menopause, so irregular menstruation is also a normal physiological manifestation, and does not require special clinical treatment. Because 49-year-old women at this time the ovarian function has declined, the menstrual cycle has been disrupted, so this time the menstrual irregularity is a manifestation of ovarian decline. If there is no clinical requirement for childbearing, it can be temporarily observed. Women’s menopause is usually at the age of 42-50 years, so 49 years old is the time of menopause. 49 years old women with irregular menstruation do not need special clinical treatment if there is no ovarian tumor, no abnormal bleeding, and no manifestation of endometrial cancer. If accompanied by heavy menstrual flow and prolonged bleeding time, it is necessary to go to the hospital for systematic examination to exclude endometrial organic lesions.