The steps of gastrointestinal decompression therapy include: insertion of a gastric tube, connection of a gastrointestinal pressure reducer, and fixation of a drainage tube. 1. Inserting gastric tube and connecting gastrointestinal pressure reducer: after inserting the gastric tube into the stomach from the oral cavity or nasal cavity, open the exhaust port of the gastrointestinal pressure reducer, exhaust the gas and connect it to the end of the gastric tube, and then the gastric contents will be drained out of the body under negative pressure and siphon principle. 2. Fixing the drainage tube: put the gastrointestinal pressure reducer in negative pressure suction state, then fix the drainage tube, and stick the mark on the end of the gastrointestinal pressure reducer. Through gastrointestinal decompression of gastric contents sucked out, can reduce the pressure in the gastrointestinal tract, reduce the degree of gastrointestinal distension, improve the blood circulation of the gastrointestinal wall, and promote the wound healing and functional recovery. During the treatment period, we must do a good job in nursing care, observing changes in the patient’s condition, and avoiding uncomfortable symptoms, so as to avoid affecting the treatment of the disease.