The pain on the soles of the feet may be caused by corns, metatarsal warts, calluses, tinea pedis, etc. Depending on the cause of the pain, medication, physical therapy, surgery, etc. may be needed. 1. corns: local skin friction and pressure caused by the phenomenon of overgrowth of the local skin stratum corneum, the local skin bumps hard, when pressed or touched with pain symptoms. They can usually be treated with medications such as salicylic acid ointment under the direction of a doctor. The more serious corns, which cause severe pain, can be treated with laser or surgical excision. 2. metatarsal warts: a special kind of common warts caused by human papilloma virus infection, the general symptoms are shiny pimples, hard texture, there will be a slight pressure and pain. Usually under the guidance of the doctor to use topical application of drugs for local treatment, such as salicylic acid ointment, etc., so that can also be used cryotherapy, laser therapy, photodynamic therapy, etc.. 3. Callus: is a long-term extrusion of the formation of keratin hyperplasia, can appear on the soles of the feet appeared cushion of flesh, with pain. Warm water can be used to soften the thickened parts, and the thickened keratin can be removed in time by rubbing with porous stone, and salicylic acid ointment can also be used to soften the thickened keratin; if it is caused by deformity of the foot, surgical correction of deformity of the foot is feasible. 4. Tinea pedis: a disease caused by fungal infection, pain may be caused by infection or cracking. Usually pay attention to avoid cleaning strength, can be used externally antifungal drugs, such as miconazole nitrate cream, terbinafine cream, etc.; serious condition can be oral antifungal drug treatment, such as itraconazole, terbinafine, etc.. The pain on the soles of the feet may also be other reasons, to go to the hospital in time to check, under the guidance of the doctor to accept the relevant treatment. The above drugs need to be used in a standardized manner under the guidance of a doctor to avoid further aggravation of the condition.