I. Comprehensive treatment of tumors Comprehensive treatment of tumors is gradually recognized and accepted by experts and scholars at home and abroad through a large number of clinical practices, and it is also a consensus formed by the academic oncology community in the course of continuous practice. Based on the patient’s systemic condition, pathological type of tumor, invasion range (stage of disease) and development trend, clinicians, after analyzing various factors in the whole body and local area, formulate a reasonable plan, apply the existing treatments in a systematic way, take advantage of the strengths and complement the weaknesses, and give full play to the integrated effect of several treatments, reduce the side-effects, and improve the quality of life, with a view to achieving the largest increase of the cure rate (the so-called “maximally increase the cure rate”). The so-called “maximally increase the cure rate” means to pay attention to the condition of the patient’s body without neglecting the specifics of the disease, and not to exclude any effective methods, and with a clear purpose). Today, the concept of integrative application of various existing methods to diagnose, prevent and treat tumors has been deeply rooted in people’s minds and accepted and recognized by a large number of scholars at home and abroad. Over the past 40 years, integrated therapy has gradually replaced traditional monotherapy, increasing the cure rate of many tumors, improving systemic control of tumors on the one hand, and making it possible to cure certain patients even if dissemination has occurred. On the other hand, it has also prompted us to have a more in-depth understanding of tumor gene regulation, growth and dissemination patterns, heterogeneity or inhomogeneity, proliferation kinetics, drug resistance (especially multidrug resistance), metabolic distribution, etc., which has promoted the development of tumor biology. Tumor therapeutic means Modern tumor therapeutic means are varied, but if applied alone, each therapy has its own advantages and disadvantages, and no new breakthrough can be made in therapeutic effect, while comprehensive tumor therapy has presented a broad prospect for development. Surgery Surgery is the first method of radical treatment of tumors. For some limited tumors, sometimes surgery alone can cure them, but most patients can not be prevented from tumor recurrence and distant metastasis by surgery alone, and some patients can not get radical effect even by “super radical surgery”. Radiotherapy Although radiotherapy can cure many kinds of tumors, it still has some limitations. If it is used together with other treatments, its efficacy can be improved to a considerable extent. Chemotherapy Chemotherapy alone is still at the level of palliative treatment for most of the tumors, but for some tumors, the cure rate has been quite high, therefore, many scholars believe that chemotherapy is in the transition from the level of palliative treatment to the level of radical treatment; however, chemotherapy also has a great disadvantage, i.e., it does not have a strong inhibitory effect on the tumor cells, and systemic medication has a greater toxicity. Chinese medicine Chinese medicine, on the other hand, has unique strengths in mobilizing the body’s resistance to disease and alleviating the side effects of other treatments, but the local control of tumors is generally poor. Biological therapy According to the understanding of tumor immunology, the new generation of biological response modifiers (BRM), its effect is level 0 kinetics, that is, a certain amount of immunoreactive cells or antibodies can eliminate a certain number of cells, while the efficacy of commonly used chemotherapy is mostly level 1 kinetics, that is, only able to kill a certain proportion of tumor cells, and people are pinning hopes on the regulation of the immune function to kill the small number of residual tumor cells, however, also It is those tumor cells that are difficult to be killed by surgery, radiotherapy or chemotherapy that can improve the cure rate of tumors. With the development of genetic engineering, it is now possible to provide a large number of high-purity cytokines, such as interferon, interleukin, colony cell stimulating factor, etc., which opens up a new way for tumor treatment.