The difference between glutamine and vitamin B₂ lies in the different indications, nature of the drug, adverse reactions, drug contraindications and so on. 1. Different indications: the main role of glutamine is to regulate autonomic function, can relieve insomnia, dreamy, poor mental health and so on. Vitamin B₂’s main role is to regulate energy metabolism, can be the treatment of keratitis lips dry cracked, tongue inflammation, accompanied by mouth ulcers and other symptoms, but also for anemic patients to replenish hematopoietic raw materials. 2. The nature of the drug is different: glutamine is mainly found in rice bran, the main chemical composition is ferulic acid ester mixture, adjusting cardiac neurosis, gastrointestinal neurosis, etc. Vitamin B₂ is a water-soluble vitamin, which is an essential element for the growth of the human body, and it can provide certain nutrition for the body’s nerves. 3. Adverse reactions are different: glutamine after medication occasionally have stomach upset, nausea, vomiting, skin rash, excessive oil secretion and other adverse reactions, can disappear after stopping the drug. Vitamin B ₂ after taking the urine is yellow, does not affect the continued use of drugs, if too much of the drug, can cause itching, burning sensation and other phenomena. 4. Different contraindications: patients with gastric and duodenal ulcers and pregnant women can not take glutathione, can not be broken during the use of glutathione or dissolved in water before taking, will increase the adverse effects of the drug. Drinking alcohol will affect the intestinal absorption of vitamin B₂, so avoid alcohol after taking vitamin B₂. Glutathione and vitamin B₂ medication, should be under the guidance of a doctor, do not stop the drug during the use of drugs, avoid drinking alcohol and spicy food.