The main causes of lateral thigh muscle pain include physiological causes and pathological causes. 1. Physiological causes: most patients with lateral thigh pain are due to muscle fatigue injury, prolonged standing and sitting, cold and other physiological causes, physiological causes will lead to anaerobic metabolism of the muscle, resulting in lactic acid, oxygen free radicals and other metabolites accumulation, stimulation of peripheral nerves leading to pain symptoms. 2. Pathologic causes: mainly including lumbar disc herniation, lateral femoral dermatitis, trauma, infection, etc. The first thing to do is to identify whether there is trauma or infection. First of all, it is necessary to clarify whether there is a history of trauma or infection; secondly, if there is a history of lumbar pain, and at the same time there are symptoms such as pain and numbness in the lower limbs, it is necessary to be highly suspicious of lumbar disc herniation; there is no uniform diagnostic standard for lateral femoral dermatomyelitis, and it is necessary for the physician to make a comprehensive assessment based on the physical examination and the auxiliary examination. Lateral thigh muscle pain may also have other causes, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.