Hand wrinkle when touching water, consider and soak time is too long, hand dehydration, ringworm and other factors. 1. Soaking time is too long: for some patients, hands wrinkled when touching water, may be due to the stratum corneum touching water after absorbing water expansion, surface area increases, and the dermis under the epidermis will not absorb water expansion, so it is easy to pile up and fold, the formation of the skin wrinkled phenomenon, and consider and soak time is too long. 2. Hand dehydration: for some patients, may not pay attention to skin moisturizing, resulting in dehydration, which will appear in the water after the symptoms of water absorption wrinkles. 3. Ringworm: when patients have ringworm disease, may cause the skin barrier function of the hand is damaged, the skin surface sebaceous membrane is damaged, resulting in the stratum corneum is easy to absorb water and swelling, touching the water on the wrinkles, most of them will also be accompanied by itching and other symptoms of the hand. Hand wrinkled when touching water may also have other reasons, need to cooperate with the doctor to clarify the specific causes before doing treatment and treatment, do not indiscriminate use of drugs.