Children with azithromycin allergy rash is a drug rash, first stop using azithromycin and seek medical attention, under the guidance of a physician to take appropriate measures. Anti-allergy treatment. Azithromycin belongs to the class of macrolide antibiotics, which is a commonly used antibacterial drug in the clinic. Azithromycin allergy in children needs to stop using azithromycin immediately and cut off the allergen. Promptly consult a doctor, under the guidance of a physician and take appropriate measures to treat, such as the use of antihistamines for anti-allergy treatment. Some reactions caused by azithromycin can be recurrent and require long-term observation and treatment. In addition, children with drug allergies need to be alert to the occurrence of laryngeal edema, once the respiratory difficulties should immediately seek medical attention to avoid life-threatening. Drugs need to be rationally applied in accordance with medical advice.