Hairy gallbladder wall does not necessarily require medication, but you can also improve the symptoms through diet. The main causes of gallbladder wall roughness are cholesterol crystallization and cholecystitis. 1. Cholesterol crystallization: Cholesterol crystallization is a sign of gallstones formation, first of all, you can make dietary adjustments, daily diet needs to be low-salt, low-sugar, low-oil diet, due to the formation of gallstones and high-salt, high-sugar, high-grease diet has a relationship with the need for dietary adjustments; you can orally cholagogue drugs, such as arbutinic acid and so on. 2. Cholecystitis: If the symptoms are mild, antibiotics can be used for anti-infective treatment, often used drugs are cephalosporin antibiotics, such as cefazolin, cefoperazone and so on. If repeated symptomatic attacks, surgical treatment is required, cholecystectomy can be performed. If surgery is not possible in the near future, percutaneous hepatic cholecystocentesis and drainage can also be performed to reduce the pressure in the gallbladder, and then surgery can be performed at a later date. If patients experience uncomfortable symptoms, it is recommended to go to the hospital in time, and follow the doctor’s instructions for medication or surgical treatment.