Quadruple therapy metronidazole usually 20mg per kilogram of body weight per day, twice a day, no more than 500mg per day, the general course of treatment is 1~2 weeks. Omeprazole is usually taken 20mg once a day, 1~2 times a day, swallowed once in the morning or once in the morning and evening, the course of treatment for gastric ulcers is usually 4~8 weeks, and the course of treatment for duodenal ulcers is usually 2~4 weeks.
Metronidazole is an antibiotic that inhibits the growth of Helicobacter pylori, and is used with another antibiotic when quadruple therapy is used to treat Helicobacter pylori-associated gastritis as well as peptic ulcers.
Common adverse reactions to metronidazole include nausea, vomiting, diarrhea, and headache. The drug is contraindicated in pregnant and lactating women, children, alcoholics, and people with metronidazole allergies.
Omeprazole is a proton pump inhibitor, can inhibit gastric acid secretion, reduce the stimulation of gastric mucosa, quadruple therapy for the treatment of gastric ulcers or duodenal ulcers can be used to protect the gastric mucosa.
Common side effects of omeprazole include weakness, drowsiness, vomiting, etc. It may also cause excessive sweating and peripheral angioedema. It is contraindicated in infants and young children, severe renal insufficiency, and patients who are allergic to the drug.
How to take metronidazole and omeprazole in quadruple therapy should be based specifically on the patient’s physical condition and reasonably under the guidance of the doctor.