Causes of obesity in the upper abdomen include irregular lifestyle, Cushing’s syndrome, hypothyroidism and so on. 1. Irregular lifestyle: long-term sedentary, and lack of exercise, long-term late night, often consume high-calorie and high-sugar foods such as meat, cream cake and other foods, often drink alcohol, overeating and other lifestyle may lead to epigastric obesity. 2. Cushing’s syndrome: the clinical manifestations of this disease are centripetal obesity, buffalo back, full moon face. Among them, centripetal obesity will lead to epigastric obesity. 3. hypothyroidism: hypothyroidism obesity is due to autoimmune system disorders and thyroxine deficiency caused by mucous edema, which can lead to epigastric obesity. Disease caused by obesity must actively treat the primary disease, and simple obesity need to control the diet, more exercise.