After the age of one year it is necessary to receive the HFMD vaccine, which protects against enterovirus 71 infection. HFMD is usually caused by infection with Coxsackievirus a16 or Enterovirus 71. The HFMD vaccine is also known as an inactivated enterovirus 71 vaccine. Vaccination against HFMD can significantly reduce the incidence of enterovirus 71 infection and thus reduce the incidence of HFMD. The enterovirus 71 vaccine can be used to prevent HFMD in infants and children between the ages of 6 months and 5 years. Vaccination against enterovirus 71 is necessary for infants and toddlers as young as one year old. In addition, infants and young children are at high risk for HFMD, so it is still necessary to vaccinate them after the age of one year, and you can consult your doctor for details.