High complex inter-sphincter type anal fistula mainly refers to the external mouth of the anal fistula is far away from the anal margin, the sinus tract of the anal fistula is more than one, and the sinus tract of the fistula passes between the external and internal sphincter of the anus. The reason for the formation is mainly inflammatory infections in the perianal area, such as repeated episodes of sinusitis, gradually penetrating outward from the perianal area, forming sinus tracts, and eventually the appearance of the external mouth and thus the formation of anal fistula. This kind of anal fistula must be treated by surgery to be able to cure. Before the operation, you need to do a perianal magnetic resonance examination to clarify the path of the sinus tract. Intraoperatively, the sinus tract is visualized with methylene blue, and the sinus tract is either completely removed or excised by hanging the sinus tract. If the sinus tract is not managed in its entirety, the recurrence rate of anal fistula is very high. High complexity sphincter between the type of anal fistula patients, in addition to surgical precautions, but also must adjust the dietary habits, avoid spicy stimulating food, avoid drinking alcohol, avoid dry stools, sedentary squatting, avoid overwork and other undesirable phenomena, otherwise the fistula is prone to recurrence. It is recommended that patients suffering from high complexity inter-sphincter type anal fistula, must go to a regular hospital, by professional doctors to assess the condition, develop a surgical plan, patients actively cooperate with the treatment, so that the cure rate will be increased, the recurrence rate will be reduced.