High Sensitivity Hepatitis B Virus Deoxyribonucleic Acid Quantitative Test <10 IU/mI indicates no detectable hepatitis B virus replication, no detectable hepatitis B virus in the blood or low viral activity. High Sensitivity Hepatitis B Virus Deoxyribonucleic Acid Quantitative Test, also known as High Sensitivity HBV-DNA Quantitative in clinical practice, is the most direct, specific and sensitive indicator of viral infection. High-sensitivity HBV-DNA <10 IU/mI means that no hepatitis B virus DNA is detected in the blood, which means no hepatitis B virus infection or low viral activity. High-sensitivity HBV-DNA quantification is mainly used to determine the level of infectiousness of hepatitis B, to evaluate the direction of disease progression of hepatitis B virus carriers, to determine the need for antiviral treatment, and to evaluate the efficacy of drug treatment. If the high sensitivity HBV DNA quantification is lower than 10IU/ml, the patient needs to be evaluated by the doctor, combined with the quantification of Hepatitis B 5 and liver function, ultrasound, liver puncture and other tests to clarify the viral replication situation and the degree of hepatocyte damage, and to formulate the treatment plan.