Nifedipine controlled-release tablets and timosartan both have antihypertensive effect, but due to the different physical condition and disease of individuals, so the antihypertensive effect will be different. 1. Nifedipine Controlled-Release Tablets: the antihypertensive effect has a fast onset, and the adverse effects of taking Nifedipine Controlled-Release Tablets include edema, headache, insomnia, dyspepsia, drowsiness, and vertigo. It is forbidden for pregnant women, lactating women and those who are allergic to any ingredients in nifedipine controlled-release tablets. 2. Timosartan: the duration of antihypertensive effect is longer, timosartan has the effect of vasoconstriction, promoting aldosterone synthesis and release, cardiac excitation and renal reabsorption of sodium, pregnant women, lactating women, patients with cardiogenic shock, and those who are allergic to any of the components of nifedipine are prohibited. Nifedipine controlled release tablets with timosartan need to be applied under the guidance of a physician.