Levodilpine is a first-line long-acting antihypertensive drug that is a calcium channel blocker. In clinical practice, it is mainly used to treat hypertension, improve angina pectoris symptoms, inhibit platelet aggregation, and indirectly lower the patient’s blood lipid level. In the process of taking this drug, patients may experience edema in the ankle, dizziness, headache, gum enlargement, and constipation. However, this drug is relatively safe and has a significant effect on lowering blood pressure. For patients with renal insufficiency, it can be used as a relatively preferred antihypertensive drug that does not affect the renal function of the patient. It is recommended that patients can take this drug for a long time, and if necessary, it can be used in combination with drugs like Irbesartan and Perindopril to lower the patient’s blood pressure, which is a relatively advantageous combination.