Painful subcutaneous laryngeal nodes are usually considered to be related to lymphadenitis, sebaceous cysts secondary infection, and subacute thyroiditis. 1. Lymphadenitis: It is usually due to the stimulation of inflammatory mediators in the lymph nodes around the laryngeal nodes and the spread of inflammation in the larynx to the external cervical lymph nodes, which leads to pain in the subcutaneous nodes of the larynx. Lymphadenitis may present with redness, swelling, and fever. 2. Sebaceous cysts secondary infection: subcutaneous laryngeal nodules may be caused by obstruction of sebaceous gland ducts under the skin of the larynx, and sebum retention to form cysts, which, if secondary infection occurs, may result in painful nodules. 3. Subacute thyroiditis: It is usually due to the swelling and pain of the thyroid gland under the stimulation of the inflammatory mediators of the thyroid gland, which causes the phenomenon of painful subcutaneous nodules in the throat. And there will be weakness, irritability and other symptoms. Painful subcutaneous nodules in the throat, it is recommended to visit the hospital for diagnosis and treatment.