Does a father with microcephaly have a child with microcephaly?

Whether a father’s child will have microcephaly depends on the specific cause of the microcephaly. If the microcephaly is secondary to certain diseases, it is not hereditary; if the microcephaly is caused by hereditary spinocerebellar ataxia, the child may have it. 1. If the microcephaly is secondary to certain acute disease processes such as the later stages of acute encephalitis, certain drug intoxication, alcohol intoxication, ischemia and hypoxia, neuroparaneoplastic syndrome, etc., and if the microcephaly is the result of certain acquired factors, it will not be inherited by the child. 2. Microcephaly is caused by spinal cerebellar ataxia, which is an autosomal dominant disease caused by abnormal amplification of the copy number of gene exon CAG to produce polyglutamine, and if the father suffers from the disease, there is a 50% probability that the child will suffer from the disease. In conclusion, if the father has microcephaly, it is recommended to visit a family planning department or fertility center for genetic eugenics counseling.