If eczema itching is severe, antihistamines are mainly given orally to relieve itching. The most commonly used antihistamines are second-generation drugs, such as loratadine, cetirizine, epalrestine, etc. However, if itching at night significantly affects rest, first-generation antihistamines can be given to help promote sleep, such as chlorpheniramine maleate, cephaeline, etc. can reduce itching and promote sleep. The choice of topical medication for eczema patients should also be based on the location and characteristics of the rash, such as the face or vulva area is best to choose drugs without hormones, such as tacrolimus, pimecrolimus, butalbital hydroxy acid, etc. can be. If the rash occurs on the extremities and trunk, glucocorticoid creams of different strengths can be given for treatment.