HIV infection red maculopapular rash is a rash that appears in the early stages of HIV infection and presents as red or dark red papules and macules. HIV infection red maculopapular rash usually appears about 2~4 weeks after the initial infection of HIV, manifesting red or dark red papules, macules, can protrude from the skin, or only skin color changes, most commonly found on the face, shoulders, neck, trunk and even the whole body can appear, usually lasts for 1-3 weeks will disappear on their own. If this papular rash appears after high-risk behavior, it is possible that you are infected by HIV and need to seek medical examination promptly. Patients with HIV red papules should actively seek medical attention, and patients should not self-medicate to avoid adverse outcomes.