High thyroid peroxidase antibodies can be caused by thyroiditis, goiter and other diseases, and treatments vary depending on the cause of the disease. 1. Thyroiditis: Thyroid peroxidase antibodies are a sensitive indicator for detecting autoimmune thyroid diseases. Patients with high thyroid peroxidase antibodies need to have further thyroid function and thyroid ultrasound examinations. If the thyroid function and thyroid ultrasound are normal, no treatment is needed and regular checkups are sufficient. If the patient has hypothyroidism, oral levothyroxine sodium tablets can be used for treatment. In addition, when the patient has pain symptoms, you can also take oral indomethacin tablets, aspirin tablets and other non-steroidal anti-inflammatory drugs as prescribed by the doctor. 2. Goiter: Goiter can also lead to the phenomenon of high thyroid peroxidase antibodies, patients can follow the doctor’s instructions to take oral methimazole and other drugs, but also for surgical treatment. If the patient has high thyroid peroxidase antibodies, he should consult a doctor in time and follow the doctor’s instructions.