The unexplainable difficulty in the chest may be caused by the following reasons: First, acute heart disease, such as acute arrhythmia, angina pectoris, myocardial infarction and other conditions, there will be more or less pain in the chest, or arrhythmia, chest tightness and other conditions, there may also feel the symptoms of palpitations. In the case of cardiogenic syncope, which can lead to dizziness, pallor, weakness of the limbs, or even fainting, it is necessary to go to the hospital immediately to check the electrocardiogram, as well as to draw blood to test the cardiac function enzyme profile to confirm the diagnosis. If an acute myocardial infarction is found, thrombolytic therapy or vascular intervention should be done immediately. Secondly, soft tissue inflammation in the chest, such as intercostal neuritis, or costochondritis, are aseptic inflammation, and can be treated with topical creams or non-steroidal anti-inflammatory drugs to reduce inflammation and pain, and the symptoms can be slowly relieved.