Blurring of the central part of the eye when looking at something is considered a loss of central vision and requires an ophthalmology visit. It may be a clouding of the central part of the refractive interstitium, or a disease of the macular region. The most common macular area disease for young people is central plasmacytochoroidal retinopathy, which usually results in a loss of central vision, as well as changes such as seeing things darker and smaller. Examination may reveal a plasma detachment in the macula, and fundus angiography, as well as OCT, may help confirm the diagnosis. The disease has a tendency to heal on its own, and laser is considered if necessary. If there is a macular fissure, it usually shows a significant loss of central vision, and OCT examination is the gold standard for diagnosis. It is more likely to occur in highly myopic as well as elderly patients and is usually treated with surgery. There are more types of disease, and examination is the key to early treatment to prevent irreversible damage.