I. Liquid of various traits and colors overflows from the opening of the milk ducts in the nipple department. Diagnosis of nipple discharge: there are clinical manifestations of nipple discharge, combined with auxiliary examination, ultrasound, lactoscopy, mammography, mammogram, mammography, magnetic resonance imaging, puncture biopsy and so on. Nipple overflow caused by different reasons and treatment principles: 1. Physiological overflow, most adult women can squeeze out a small amount of liquid through breast massage and mild squeezing and suction, which is physiologically secreted. The color is varied, the vast majority is colorless and transparent, milk-like, yellowish, a few can be green, brown, dark blue. This physiologic overflow is mostly multicatheteric. In this case, patients do not need to worry, and do not need special treatment. 2, pharmacological overflow, taking certain drugs, such as psychotropic drugs phenothiazine, haloperidol, etc., some anti-hypertensive drugs such as methyldopa, rifampicin, opioid preparations, drugs containing estrogen, etc.. There is no need to worry about this condition and no treatment is needed. 3.Intraductal papilloma, the most common cause of plasma or bloody overflow, the tumor occurs in larger subareolar ducts. Although some researchers believe that single papilloma should not be regarded as precancerous lesion, surgery is still a necessary option, which usually requires excision of the diseased duct or removal of tiny nodules. 4.Multiple intraductal papillomas, about 10% of intraductal papillomas are multiple, which can be multiple nodules in one duct or multiple nodules in multiple ducts. Some studies have proved that multiple intraductal papillomas are associated with increased risk of breast cancer. Surgery is necessary and usually requires lesion ductal resection or segmental mastectomy. 5.Breast cancer, invasive cancer and non-invasive cancer can cause nipple discharge, but ductal carcinoma in situ is more common, and it is very rare that invasive cancer causes nipple discharge without detecting breast lump. If nipple discharge is the first or main symptom and diagnosed as breast cancer in auxiliary examination, it will be further treated according to the treatment principle of breast cancer. 6.Bloody nipple discharge during pregnancy, nipple discharge containing blood during pregnancy or breastfeeding is common, the possible reason is the excessive blood vessels in the developing breast tissue during this period, this situation is benign and does not need special treatment. 7, breast overflow (or overflow), bilateral milk-like overflow unrelated to pregnancy or breastfeeding is known as breast overflow. A small amount of milk overflow, caused by squeezing does not indicate a serious problem and can be observed. A large amount of breastfeeding is often caused by elevated prolactin, a significant increase in prolactin is a drug problem, in addition to consider the possibility of pituitary prolactin microadenoma, if necessary, you can perform a cranial magnetic resonance examination to clarify, but to avoid a small amount of breastfeeding or extrusion caused by breastfeeding over the magnetic resonance examination of the problem (magnetic resonance examination is still relatively expensive), the pituitary lactin microadenoma is not a serious problem, it is a benign small tumor, there are no symptoms. A small benign tumor, no symptoms are not dealt with, and when accompanying symptoms occur, a minor surgery in neurosurgery can solve the problem. Hyperprolactinemia drug treatment is mainly oral bromocriptine. 8, ductal dilatation, some women because of ductal dilatation and nipple overflow, mostly colorless or yellowish liquid, can also be manifested as viscous, toothpaste-like, or even cheese-like overflow. Duct dilatation generally does not require treatment, unless the persistent overflow, the amount is large, bring obvious life inconvenience, surgery can also be considered, overflow nipple duct breakage excision, very small surgery. Fourth, in short, nipple overflow is a benign manifestation in most cases. Malignant pathological causes of the overflow is rare, so, the nipple overflow we do not have to worry, to the regular hospital breast specialist check, obey the doctor’s diagnosis and treatment advice can be.