Colds with yellow water from the nose can be seen in acute rhinitis caused by bacterial infection, chronic rhinitis, sinusitis and so on. At this time, you can test the blood routine, head CT, but also can do nasal endoscopy. If necessary, you can also take the nasal mucus for pathogen culture and drug sensitivity test, to clarify the specific types of pathogens and sensitive anti-inflammatory drugs. Anti-bacterial drugs such as penicillin, amoxicillin, cefuroxime, cefoperazone, erythromycin, azithromycin, roxithromycin and other drugs can be chosen for treatment.