Metronidazole caused gastrointestinal nausea can be adjusted to the time of medication, the use of alternative medication, adjuvant medication and so on. Nausea after using metronidazole, generally related to its side effects, metronidazole can stimulate the gastric mucosa, which leads to discomfort, if the symptoms are mild, no special treatment; if the symptoms are more serious, you can replace the treatment with other drugs or use some drugs to protect the gastric mucosa to relieve nausea, vomiting. 1. Adjusting the time of medication: If the patient only has mild nausea or gastrointestinal discomfort, he can drink more water and adjust the time of medication, such as taking it after meals, so as to reduce the stimulation of the gastric mucosa of the drug. 2. Alternative drug therapy: If the patient’s nausea, vomiting, gastrointestinal pain and other symptoms are obvious and continue to be unrelieved, you can switch to drugs with a similar function to metronidazole, such as tinidazole, tinidazole on the gastrointestinal tract, the side effects of the lighter. 3. Auxiliary drug therapy: if the patient’s gastrointestinal discomfort, nausea, etc., you can use some drugs to protect the gastric mucosa, such as magnesium alumina carbonate tablets, and then relieve nausea, vomiting and other symptoms. It is worth noting that patients taking metronidazole, should pay attention to reasonable diet to minimize the stimulation of the gastric mucosa. If the symptoms of gastrointestinal nausea are not relieved, or accompanied by other symptoms, you should go to the hospital in a timely manner, under the guidance of the doctor to adjust the drug.